In the sixth episode of the 2016 TV series, Manboy attempts to destroy the Zen-Aissance Fair using his Manbot, but is intercepted by Buttercup, who he enrages by calling her princess. His Man-bot puts up a fight for a short period but is ultimately destroyed by Buttercup who throws Manboy across the city. Manboy is seen later in his dwelling, plotting revenge against Buttercup. While there he carves wooden heads of the Powerpuff Girls using his chainsaw, with Buttercup at the top. Out of anger, Manboy throws his chainsaw at the Buttercup carving, but it simply bounces off, to Manboy's grief.
He later returns to the Zen-Aissance Fair with a wooden cannon being pulled by a polar bear and an army of animated T-bone steaks. Buttercup, who has converted to a more peaceful state of being, simply puts a flower in the cannon and is shot by it. When Blossom and Bubbles are having trouble defeating Manboy's meat army, Buttercup uses the training she learned from Guru Chillaxi to defeat Manboy, burning his beard off with her heat vision and tossing him into a giant pile of tofu.